In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2

Hepcidin is the principal iron-regulatory hormone and a pathogenic factor in anemia of inflammation. Patients with multiple myeloma (MM) frequently present with anemia. We showed that MM patients had increased serum hepcidin, which inversely correlated with hemoglobin, suggesting that hepcidin contr...

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Autori principali: Maes, Ken, Nemeth, Elizabeta, Roodman, G. David, Huston, Alissa, Esteve, Flavia, Freytes, Cesar, Callander, Natalie, Katodritou, Eirini, Tussing-Humphreys, Lisa, Rivera, Seth, Vanderkerken, Karin, Lichtenstein, Alan, Ganz, Tomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Red Cells, Iron, and Erythropoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981483/
https://ncbi.nlm.nih.gov/pubmed/20679527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-274571
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