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Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

The proton-coupled folate transporter (PCFT-SLC46A1) is required for intestinal folate absorption and is mutated in the autosomal recessive disorder, hereditary folate malabsorption (HFM). This report characterizes properties and requirements of the R376 residue in PCFT function, including a R376Q m...

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Detaylı Bibliyografya
Asıl Yazarlar: Mahadeo, Kris, Diop-Bove, Ndeye, Shin, Daniel, Unal, Ersin Selcuk, Teo, Juliana, Zhao, Rongbao, Chang, Min-Hwang, Fulterer, Andreas, Romero, Michael F., Goldman, I. David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980313/
https://ncbi.nlm.nih.gov/pubmed/20686069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00113.2010
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