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Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

The proton-coupled folate transporter (PCFT-SLC46A1) is required for intestinal folate absorption and is mutated in the autosomal recessive disorder, hereditary folate malabsorption (HFM). This report characterizes properties and requirements of the R376 residue in PCFT function, including a R376Q m...

詳細記述

保存先:
書誌詳細
主要な著者: Mahadeo, Kris, Diop-Bove, Ndeye, Shin, Daniel, Unal, Ersin Selcuk, Teo, Juliana, Zhao, Rongbao, Chang, Min-Hwang, Fulterer, Andreas, Romero, Michael F., Goldman, I. David
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980313/
https://ncbi.nlm.nih.gov/pubmed/20686069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00113.2010
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