Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.
Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression. We used the polymerase chain reaction technique to amplify and clone an 882-base-pair DNA fragment s...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1989
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2780563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7082 |
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