Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression. We used the polymerase chain reaction technique to amplify and clone an 882-base-pair DNA fragment s...

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Detalhes bibliográficos
Main Authors: Curtin, P T, Liu, D P, Liu, W, Chang, J C, Kan, Y W
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC297998/
https://ncbi.nlm.nih.gov/pubmed/2780563
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