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Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice.

Previous experiments have demonstrated that the human beta-globin gene is correctly regulated in transgenic mice. The beta-globin gene is not expressed in yolk sac-derived erythroid cells in early embryonic development but is expressed concomitantly with the adult mouse beta-globin genes in 14- to 1...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Behringer, R R, Hammer, R E, Brinster, R L, Palmiter, R D, Townes, T M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3478680/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.20.7056
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