Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice.
Previous experiments have demonstrated that the human beta-globin gene is correctly regulated in transgenic mice. The beta-globin gene is not expressed in yolk sac-derived erythroid cells in early embryonic development but is expressed concomitantly with the adult mouse beta-globin genes in 14- to 1...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299228/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3478680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.20.7056 |
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