Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site.

Several lines of evidence suggest that erythroid-specific DNase I hypersensitive sites (HS) located far upstream of the human beta-globin gene are important in regulating beta-globin gene expression. We used the polymerase chain reaction technique to amplify and clone an 882-base-pair DNA fragment s...

Descripción completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Curtin, P T, Liu, D P, Liu, W, Chang, J C, Kan, Y W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2780563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.18.7082
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!