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Functional Redundancy of Steroid C(26)-monooxygenase Activity in Mycobacterium tuberculosis Revealed by Biochemical and Genetic Analyses
One challenge to the development of new antitubercular drugs is the existence of multiple virulent strains that differ genetically. We and others have recently demonstrated that CYP125A1 is a steroid C(26)-monooxygenase that plays a key role in cholesterol catabolism in Mycobacterium tuberculosis CD...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978563/ https://ncbi.nlm.nih.gov/pubmed/20843794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161117 |
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