Functional Redundancy of Steroid C(26)-monooxygenase Activity in Mycobacterium tuberculosis Revealed by Biochemical and Genetic Analyses

One challenge to the development of new antitubercular drugs is the existence of multiple virulent strains that differ genetically. We and others have recently demonstrated that CYP125A1 is a steroid C(26)-monooxygenase that plays a key role in cholesterol catabolism in Mycobacterium tuberculosis CD...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Johnston, Jonathan B., Ouellet, Hugues, de Montellano, Paul R. Ortiz
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Enzymology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978563/
https://ncbi.nlm.nih.gov/pubmed/20843794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161117
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items