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Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that infects 10 million worldwide and kills 2 million people every year. The uptake and utilization of nutrients by Mtb within the host cell is still poorly understood, although lipids play an important role in Mtb persistence. The recent...

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Detalhes bibliográficos
Main Authors: Ouellet, Hugues, Johnston, Jonathan B., Ortiz de Montellano, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205253/
https://ncbi.nlm.nih.gov/pubmed/21924910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2011.07.009
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