Loading...
Inhibition of Short Patch and Long Patch Base Excision Repair by an Oxidized Abasic Site
5′-(2-Phosphoryl-1,4-dioxobutane) (DOB) is an oxidized abasic lesion that is produced by a variety of DNA damaging agents, including several antitumor antibiotics. DOB efficiently, and irreversibly inhibits DNA polymerase β, an essential base excision repair enzyme in mammalian cells. The generality...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976803/ https://ncbi.nlm.nih.gov/pubmed/20961055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101533a |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|