Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics

The goal of this study was to determine the effects of genetic variation in the organic cation transporter 1, OCT1, on the pharmacokinetics of the antidiabetic drug, metformin. Twenty healthy volunteers with known OCT1 genotype agreed to participate in the study. Each subject received two oral doses...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Shu, Y, Brown, C, Castro, RA, Shi, RJ, Lin, ET, Owen, RP, Sheardown, SA, Yue, L, Burchard, EG, Brett, CM, Giacomini, KM
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976713/
https://ncbi.nlm.nih.gov/pubmed/17609683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.clpt.6100275
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky