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Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics

The goal of this study was to determine the effects of genetic variation in the organic cation transporter 1, OCT1, on the pharmacokinetics of the antidiabetic drug, metformin. Twenty healthy volunteers with known OCT1 genotype agreed to participate in the study. Each subject received two oral doses...

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Detaylı Bibliyografya
Asıl Yazarlar: Shu, Y, Brown, C, Castro, RA, Shi, RJ, Lin, ET, Owen, RP, Sheardown, SA, Yue, L, Burchard, EG, Brett, CM, Giacomini, KM
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976713/
https://ncbi.nlm.nih.gov/pubmed/17609683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.clpt.6100275
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