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OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans
Organic cation transporter 3 (OCT3) is expressed in various organs in humans and plays an important role in the transport of organic cations and drugs including metformin. In this study, we identified genetic variations of the OCT3 promoter and functionally characterized each variant by in vitro ass...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240047/ https://ncbi.nlm.nih.gov/pubmed/30446679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35322-6 |
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