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Domain motion and interdomain hot spots in a multidomain enzyme

The aim of this article is to analyze conformational changes by comparing 10 different structures of Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase (PMM/PGM), a four-domain enzyme in which both substrate binding and catalysis require substantial movement of the C-terminal domain. We fo...

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Bibliografische gegevens
Hoofdauteurs: Chuang, Gwo-Yu, Mehra-Chaudhary, Ritcha, Ngan, Chi-Ho, Zerbe, Brandon S, Kozakov, Dima, Vajda, Sandor, Beamer, Lesa J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley Subscription Services, Inc., A Wiley Company 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975130/
https://ncbi.nlm.nih.gov/pubmed/20589904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.446
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