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Domain motion and interdomain hot spots in a multidomain enzyme
The aim of this article is to analyze conformational changes by comparing 10 different structures of Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase (PMM/PGM), a four-domain enzyme in which both substrate binding and catalysis require substantial movement of the C-terminal domain. We fo...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975130/ https://ncbi.nlm.nih.gov/pubmed/20589904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.446 |
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