Nanoparticle-induced vascular blockade in human prostate cancer

The tumor-homing pentapeptide CREKA (Cys-Arg-Glu-Lys-Ala) specifically homes to tumors by binding to fibrin and fibrin-associated clotted plasma proteins in tumor vessels. Previous results show that CREKA-coated superparamagnetic iron oxide particles can cause additional clotting in tumor vessels, w...

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Detalhes bibliográficos
Main Authors: Agemy, Lilach, Sugahara, Kazuki N., Kotamraju, Venkata Ramana, Gujraty, Kunal, Girard, Olivier M., Kono, Yuko, Mattrey, Robert F., Park, Ji-Ho, Sailor, Michael J., Jimenez, Ana I., Cativiela, Carlos, Zanuy, David, Sayago, Francisco J., Aleman, Carlos, Nussinov, Ruth, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974592/
https://ncbi.nlm.nih.gov/pubmed/20587786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-274258
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