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Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution
[Image: see text] The partial unfolding of human lysozyme underlies its conversion from the soluble state into amyloid fibrils observed in a fatal hereditary form of systemic amyloidosis. To understand the molecular origins of the disease, it is critical to characterize the structural and physicoche...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974344/ https://ncbi.nlm.nih.gov/pubmed/20958028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103524m |
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