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The Non-Core Regions of Human Lysozyme Amyloid Fibrils Influence Cytotoxicity

Identifying the cause of the cytotoxicity of species populated during amyloid formation is crucial to understand the molecular basis of protein deposition diseases. We have examined different types of aggregates formed by lysozyme, a protein found as fibrillar deposits in patients with familial syst...

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Main Authors: Mossuto, Maria F., Dhulesia, Anne, Devlin, Glyn, Frare, Erica, Kumita, Janet R., de Laureto, Patrizia Polverino, Dumoulin, Mireille, Fontana, Angelo, Dobson, Christopher M., Salvatella, Xavier
格式: Artigo
語言:Inglês
出版: Elsevier 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954362/
https://ncbi.nlm.nih.gov/pubmed/20624399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.005
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