Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Damaging interactions between antibodies and brain antigenic targets may be responsible for an expanding range of neurological disorders. In the case of systemic lupus erythematosus (SLE), patients generate autoantibodies (AAbs) that frequently bind dsDNA. Although some symptoms of SLE may arise fro...

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Detalhes bibliográficos
Main Authors: Faust, Thomas W., Chang, Eric H., Kowal, Czeslawa, Berlin, RoseAnn, Gazaryan, Irina G., Bertini, Eva, Zhang, Jie, Sanchez-Guerrero, Jorge, Fragoso-Loyo, Hilda E., Volpe, Bruce T., Diamond, Betty, Huerta, Patricio T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972998/
https://ncbi.nlm.nih.gov/pubmed/20921396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006980107
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