Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms

Damaging interactions between antibodies and brain antigenic targets may be responsible for an expanding range of neurological disorders. In the case of systemic lupus erythematosus (SLE), patients generate autoantibodies (AAbs) that frequently bind dsDNA. Although some symptoms of SLE may arise fro...

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Hlavní autoři: Faust, Thomas W., Chang, Eric H., Kowal, Czeslawa, Berlin, RoseAnn, Gazaryan, Irina G., Bertini, Eva, Zhang, Jie, Sanchez-Guerrero, Jorge, Fragoso-Loyo, Hilda E., Volpe, Bruce T., Diamond, Betty, Huerta, Patricio T.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972998/
https://ncbi.nlm.nih.gov/pubmed/20921396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006980107
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