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Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor

Patients with systemic lupus erythematosus (SLE) experience cognitive abnormalities in multiple domains including processing speed, executive function, and memory. Here we show that SLE patients carrying antibodies that bind DNA and the GluN2A and GluN2B subunits of the N-methyl-d-aspartate receptor...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Chang, Eric H., Volpe, Bruce T., Mackay, Meggan, Aranow, Cynthia, Watson, Philip, Kowal, Czeslawa, Storbeck, Justin, Mattis, Paul, Berlin, RoseAnn, Chen, Huiyi, Mader, Simone, Huerta, Tomás S., Huerta, Patricio T., Diamond, Betty
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534689/
https://ncbi.nlm.nih.gov/pubmed/26286205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.05.027
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