Selective Impairment of Spatial Cognition Caused by Autoantibodies to the N-Methyl-d-Aspartate Receptor

Patients with systemic lupus erythematosus (SLE) experience cognitive abnormalities in multiple domains including processing speed, executive function, and memory. Here we show that SLE patients carrying antibodies that bind DNA and the GluN2A and GluN2B subunits of the N-methyl-d-aspartate receptor...

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Publicado en:EBioMedicine
Autores principales: Chang, Eric H., Volpe, Bruce T., Mackay, Meggan, Aranow, Cynthia, Watson, Philip, Kowal, Czeslawa, Storbeck, Justin, Mattis, Paul, Berlin, RoseAnn, Chen, Huiyi, Mader, Simone, Huerta, Tomás S., Huerta, Patricio T., Diamond, Betty
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534689/
https://ncbi.nlm.nih.gov/pubmed/26286205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.05.027
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