Human lupus autoantibodies against NMDA receptors mediate cognitive impairment

Neuropsychiatric systemic lupus erythematosus, which often entails cognitive disturbances and memory loss, has become a major complication for lupus patients. Previously, we developed a murine model of neuropsychiatric lupus based on Abs that cross-react with dsDNA and the NMDA receptor (NMDAR). We...

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Detalhes bibliográficos
Main Authors: Kowal, Czeslawa, DeGiorgio, Lorraine A., Lee, Ji Y., Edgar, Mark A., Huerta, Patricio T., Volpe, Bruce T., Diamond, Betty
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702320/
https://ncbi.nlm.nih.gov/pubmed/17170137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608397104
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