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Polyreactive autoantibodies in systemic lupus erythematosus have pathogenic potential
The present study was undertaken to determine whether germline encoded and polyreactive antibodies might be pathogenic and whether the breach of early tolerance checkpoints in Systemic Lupus Erythematosus (SLE) might lead to a population of B cells expressing germline encoded antibodies that become...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783480/ https://ncbi.nlm.nih.gov/pubmed/19398190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.03.011 |
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