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Polyreactive autoantibodies in systemic lupus erythematosus have pathogenic potential

The present study was undertaken to determine whether germline encoded and polyreactive antibodies might be pathogenic and whether the breach of early tolerance checkpoints in Systemic Lupus Erythematosus (SLE) might lead to a population of B cells expressing germline encoded antibodies that become...

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Dettagli Bibliografici
Autori principali: Zhang, Jie, Jacobi, Annett M., Wang, Tao, Berlin, RoseAnn, Volpe, Bruce, Diamond, Betty
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783480/
https://ncbi.nlm.nih.gov/pubmed/19398190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.03.011
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