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Hemoglobin synthesis in β-thalassemia: the properties of the free α-chains
The decrease in hemoglobin A (HbA, α(2)β(2)) synthesis in the erythroid cells of patients with β-thalassemia is due to a selective defect in β-chain synthesis. Since α-chains continue to be formed at a normal rate in these cells, this results in a marked relative excess of α-chain synthesis over β-...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1968
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC297235/ https://ncbi.nlm.nih.gov/pubmed/5641622 |
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