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Synthesis of hemoglobin Gun Hill: increased synthesis of the heme-free β(GH) globin chain and subunit exchange with a free α-chain pool
Hemoglobin Gun Hill is an unstable mutant hemoglobin associated with mild compensated hemolysis. This abnormal protein has a deletion of five amino acids in the β-chains. The deletion includes the heme-binding proximal histidine at position 92. The β-chains of hemoglobin Gun Hill lack heme groups. A...
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| Publicado no: | J Clin Invest |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC291935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5540175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106506 |
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