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An erythroid chaperone that facilitates folding of α-globin subunits for hemoglobin synthesis
Erythrocyte precursors produce abundant α- and β-globin proteins, which assemble with each other to form hemoglobin A (HbA), the major blood oxygen carrier. αHb-stabilizing protein (AHSP) binds free α subunits reversibly to maintain their structure and limit their ability to generate reactive oxygen...
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| Asıl Yazarlar: | , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1904324/ https://ncbi.nlm.nih.gov/pubmed/17607360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31664 |
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