An erythroid chaperone that facilitates folding of α-globin subunits for hemoglobin synthesis

Erythrocyte precursors produce abundant α- and β-globin proteins, which assemble with each other to form hemoglobin A (HbA), the major blood oxygen carrier. αHb-stabilizing protein (AHSP) binds free α subunits reversibly to maintain their structure and limit their ability to generate reactive oxygen...

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Главные авторы: Yu, Xiang, Kong, Yi, Dore, Louis C., Abdulmalik, Osheiza, Katein, Anne M., Zhou, Suiping, Choi, John K., Gell, David, Mackay, Joel P., Gow, Andrew J., Weiss, Mitchell J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2007
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904324/
https://ncbi.nlm.nih.gov/pubmed/17607360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31664
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