A cis-Proline in α-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of α-Hemoglobin

α-Hemoglobin (αHb) stabilizing protein (AHSP) is expressed in erythropoietic tissues as an accessory factor in hemoglobin synthesis. AHSP forms a specific complex with αHb and suppresses the heme-catalyzed evolution of reactive oxygen species by converting αHb to a conformation in which the heme is...

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Detalhes bibliográficos
Main Authors: Gell, David A., Feng, Liang, Zhou, Suiping, Jeffrey, Philip D., Bendak, Katerina, Gow, Andrew, Weiss, Mitchell J., Shi, Yigong, Mackay, Joel P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785579/
https://ncbi.nlm.nih.gov/pubmed/19706593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027045
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