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Synthesis of hemoglobin Gun Hill: increased synthesis of the heme-free β(GH) globin chain and subunit exchange with a free α-chain pool
Hemoglobin Gun Hill is an unstable mutant hemoglobin associated with mild compensated hemolysis. This abnormal protein has a deletion of five amino acids in the β-chains. The deletion includes the heme-binding proximal histidine at position 92. The β-chains of hemoglobin Gun Hill lack heme groups. A...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1971
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291935/ https://ncbi.nlm.nih.gov/pubmed/5540175 |
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