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Free Heme and the Polymerization of Sickle Cell Hemoglobin
In search of novel control parameters for the polymerization of sickle cell hemoglobin (HbS), the primary pathogenic event of sickle cell anemia, we explore the role of free heme, which may be excessively released in sickle erythrocytes. We show that the concentration of free heme in HbS solutions t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941010/ https://ncbi.nlm.nih.gov/pubmed/20858444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.024 |
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