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Liquid–liquid separation in solutions of normal and sickle cell hemoglobin
We show that in solutions of human hemoglobin (Hb)—oxy- and deoxy-Hb A or S—of near-physiological pH, ionic strength, and Hb concentration, liquid–liquid phase separation occurs reversibly and reproducibly at temperatures between 35 and 40°C. In solutions of deoxy-HbS, we demonstrate that the dense...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124280/ https://ncbi.nlm.nih.gov/pubmed/12070342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122055299 |
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