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Phase Separation and Crystallization of Hemoglobin C in Transgenic Mouse and Human Erythrocytes

Individuals expressing hemoglobin C (β6 Glu→Lys) present red blood cells (RBC) with intraerythrocytic crystals that form when hemoglobin (Hb) is oxygenated. Our earlier in vitro liquid-liquid (L-L) phase separation studies demonstrated that liganded HbC exhibits a stronger net intermolecular attract...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Canterino, Joseph E., Galkin, Oleg, Vekilov, Peter G., Hirsch, Rhoda Elison
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553125/
https://ncbi.nlm.nih.gov/pubmed/18621841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127324
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