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Phase Separation and Crystallization of Hemoglobin C in Transgenic Mouse and Human Erythrocytes
Individuals expressing hemoglobin C (β6 Glu→Lys) present red blood cells (RBC) with intraerythrocytic crystals that form when hemoglobin (Hb) is oxygenated. Our earlier in vitro liquid-liquid (L-L) phase separation studies demonstrated that liganded HbC exhibits a stronger net intermolecular attract...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2553125/ https://ncbi.nlm.nih.gov/pubmed/18621841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.127324 |
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