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Understanding globin regulation in β-thalassemia: it’s as simple as α, β, γ, δ

A vast excess of α-globin production and inadequate γ-globin compensation lead to the development of severe anemia in human β-thalassemia. Newly identified modifiers of α- and γ-globin synthesis and insights into the mechanisms of globin regulation provide the tools for potential new approaches to t...

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Bibliografski detalji
Glavni autor: Bank, Arthur
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137010/
https://ncbi.nlm.nih.gov/pubmed/15931385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25398
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