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Equal synthesis of α- and β-globin chains in erythroid precursors in heterozygous β-thalassemia

In patients with heterozygous β-thalassemia, the β/α synthetic ratio in marrow erythroid cells incubated in vitro is 1, whereas in reticulocytes the ratio is 0.5. These ratios reflect the equal synthesis of the two chains on the polyribosomes of the bone marrow and unequal synthesis on the polyribos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kan, Yuet Wai, Nathan, David G., Lodish, Harvey F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1972
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC292339/
https://ncbi.nlm.nih.gov/pubmed/5032531
Etiketak: Etiketa erantsi
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