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Loss of PHD Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy

BACKGROUND: Ischemic cardiomyopathy is the major cause of heart failure and a significant cause of morbidity and mortality. The degree of left ventricular dysfunction in this setting is often out of proportion to the amount of overtly infarcted tissue and how decreased delivery of oxygen and nutrien...

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Detalhes bibliográficos
Main Authors: Moslehi, Javid, Minamishima, Yoji Andrew, Shi, Jianru, Neuberg, Donna, Charytan, David, Padera, Robert F., Signoretti, Sabina, Liao, Ronglih, Kaelin, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2971656/
https://ncbi.nlm.nih.gov/pubmed/20733101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.922427
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