Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common and comprehensively studied malignancies. Hypoxic conditions during formation of CRC may support the development of more aggressive cancers. Hypoxia inducible factor (HIF), a major player in cancerous tissue adaptation to hypoxia, is nega...

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Bibliografske podrobnosti
Main Authors: Rawluszko, Agnieszka A, Bujnicka, Katarzyna E, Horbacka, Karolina, Krokowicz, Piotr, Jagodziński, Paweł P
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828400/
https://ncbi.nlm.nih.gov/pubmed/24195777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-526
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