Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is one of the most common and comprehensively studied malignancies. Hypoxic conditions during formation of CRC may support the development of more aggressive cancers. Hypoxia inducible factor (HIF), a major player in cancerous tissue adaptation to hypoxia, is nega...

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Bibliographic Details
Main Authors: Rawluszko, Agnieszka A, Bujnicka, Katarzyna E, Horbacka, Karolina, Krokowicz, Piotr, Jagodziński, Paweł P
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828400/
https://ncbi.nlm.nih.gov/pubmed/24195777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-526
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