p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

PINK1 and Parkin were first identified as the causal genes responsible for familial forms of early-onset Parkinson’s disease (PD), a prevalent neurodegenerative disorder. PINK1 encodes a mitochondrial serine/threonine protein kinase, whereas Parkin encodes an ubiquitin-protein ligase. PINK1 and Park...

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Autors principals: Okatsu, Kei, Saisho, Keiko, Shimanuki, Midori, Nakada, Kazuto, Shitara, Hiroshi, Sou, Yu-shin, Kimura, Mayumi, Sato, Shigeto, Hattori, Nobutaka, Komatsu, Masaaki, Tanaka, Keiji, Matsuda, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970908/
https://ncbi.nlm.nih.gov/pubmed/20604804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2443.2010.01426.x
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