T CELL IMMUNOGLOBULIN MUCIN-3 DICTATES SEVERITY OF LIVER ISCHEMIA/ REPERFUSION INJURY IN MICE IN TLR4-DEPENDENT MANNER

The newly discovered T-cell immunoglobulin mucin (TIM) gene family molecules, expressed by T cells, regulate host immunity and tolerance. Although CD4(+) T cells mediate innate immunity-dominated liver ischemia-reperfusion injury (IRI), the underlying mechanisms remain obscure. We have recently docu...

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Detalhes bibliográficos
Main Authors: Uchida, Yoichiro, Ke, Bibo, Freitas, Maria Cecilia S, Yagita, Hideo, Akiba, Hisaya, Busuttil, Ronald W, Najafian, Nader, Kupiec-Weglinski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970711/
https://ncbi.nlm.nih.gov/pubmed/20637206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.07.003
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