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The Protective Function of Neutrophil Elastase Inhibitor in Liver Ischemia and Reperfusion Injury

BACKGROUND: A neutrophil elastase (NE) inhibitor, Sivelestat, has been approved for the treatment of acute lung injury associated with systemic inflammation in humans. Some reports have also shown its protective effects in liver inflammatory states. We have recently documented the importance of NE i...

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Detalhes bibliográficos
Main Authors: Uchida, Yoichiro, Freitas, Maria Cecilia S., Zhao, Danyun, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627371/
https://ncbi.nlm.nih.gov/pubmed/20160675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181d45a98
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