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The Protective Function of Neutrophil Elastase Inhibitor in Liver Ischemia and Reperfusion Injury

BACKGROUND: A neutrophil elastase (NE) inhibitor, Sivelestat, has been approved for the treatment of acute lung injury associated with systemic inflammation in humans. Some reports have also shown its protective effects in liver inflammatory states. We have recently documented the importance of NE i...

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Autori principali: Uchida, Yoichiro, Freitas, Maria Cecilia S., Zhao, Danyun, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627371/
https://ncbi.nlm.nih.gov/pubmed/20160675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181d45a98
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