PD-1 – B7-H1 NEGATIVE CO-STIMULATION PROTECTS MOUSE LIVER AGAINST ISCHEMIA AND REPERFUSION INJURY

Programmed Death-1 (PD-1)/B7-H1 co-stimulation acts as negative regulator of host allo-immune responses. Although CD4 T cells mediate innate immunity-dominated ischemia/reperfusion injury (IRI) in the liver, the underlying mechanisms remain to be elucidated. This study focuses on the role of PD-1/B7...

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Detalhes bibliográficos
Main Authors: Ji, Haofeng, Shen, Xiuda, Gao, Feng, Ke, Bibo, Freitas, Maria Cecilia S., Uchida, Yoichiro, Busuttil, Ronald W., Zhai, Yuan, Kupiec-Weglinski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947605/
https://ncbi.nlm.nih.gov/pubmed/20815020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23843
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