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The Inhibition of Neutrophil Elastase Ameliorates Mouse Liver Damage Due to Ischemia and Reperfusion

Neutrophils are considered crucial effector cells in the pathophysiology of organ ischemia/reperfusion injury (IRI). Although neutrophil elastase (NE) accounts for a substantial portion of the neutrophil activity, the function of NE in liver IRI remains unclear. This study focuses on the role of NE...

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Main Authors: Uchida, Yoichiro, Freitas, Maria Cecilia S., Zhao, Danyun, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752954/
https://ncbi.nlm.nih.gov/pubmed/19642132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.21770
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