PTEN-MEDIATEDAKT/β-CATENIN/FOXO1 SIGNALING REGULATES INNATE IMMUNE RESPONSES IN MOUSE LIVER ISCHEMIA/REPERFUSION INJURY

The phosphatase and tensin homolog delete on chromosome 10 (PTEN) regulates innate immune responses inversely with phosphoinositide 3-kinase (PI3K) and its direct downstream target gene, Akt. The Forkhead box O (Foxo) transcription factors are essential in the regulation of tissue development, immun...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kamo, Naoko, Ke, Bibo, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3524373/
https://ncbi.nlm.nih.gov/pubmed/22807038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25958
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