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PTEN-MEDIATEDAKT/β-CATENIN/FOXO1 SIGNALING REGULATES INNATE IMMUNE RESPONSES IN MOUSE LIVER ISCHEMIA/REPERFUSION INJURY
The phosphatase and tensin homolog delete on chromosome 10 (PTEN) regulates innate immune responses inversely with phosphoinositide 3-kinase (PI3K) and its direct downstream target gene, Akt. The Forkhead box O (Foxo) transcription factors are essential in the regulation of tissue development, immun...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3524373/ https://ncbi.nlm.nih.gov/pubmed/22807038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25958 |
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