HO-1 - STAT3 Axis in Mouse Liver Ischemia/Reperfusion Injury: Regulation of TLR4 Innate Responses Through PI3K/PTEN Signaling

BACKGROUND&AIM: Signal transducer and activator of transcription 3 (STAT3), a key mediator of anti-inflammatory cytokine signaling, is essential for heme oxygenase-1 (HO-1)-induced cytoprotection. The phosphoinositide 3-kinase (PI3K)/phosphatase and tensin homolog delete on chromosome 10 (PTEN)...

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Main Authors: Ke, Bibo, Shen, Xiu-Da, Ji, Haofeng, Kamo, Naoko, Gao, Feng, Freitas, Maria Cecilia S., Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444295/
https://ncbi.nlm.nih.gov/pubmed/21756853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2011.05.023
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