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Sotrastaurin, a Protein Kinase C Inhibitor, Ameliorates Ischemia and Reperfusion Injury in Rat Orthotopic Liver Transplantation
Sotraustaurin (STN), a small molecule, targeted PKC inhibitor that prevents T lymphocyte activation via a calcineurin-independent pathway, is currently tested in Phase II renal and liver transplantation clinical trials. We have documented the key role of activated T cells in the inflammation cascade...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625141/ https://ncbi.nlm.nih.gov/pubmed/21883905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03700.x |
| תגים: |
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