Sotrastaurin, a Protein Kinase C Inhibitor, Ameliorates Ischemia and Reperfusion Injury in Rat Orthotopic Liver Transplantation

Sotraustaurin (STN), a small molecule, targeted PKC inhibitor that prevents T lymphocyte activation via a calcineurin-independent pathway, is currently tested in Phase II renal and liver transplantation clinical trials. We have documented the key role of activated T cells in the inflammation cascade...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kamo, Naoko, Shen, Xiu-da, Ke, Bibo, Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625141/
https://ncbi.nlm.nih.gov/pubmed/21883905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03700.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker