Small Interfering RNA Targeting Heme Oxygenase-1 (HO-1) Reinforces Liver Apoptosis Induced by Ischemia–Reperfusion Injury in Mice: HO-1 Is Necessary for Cytoprotection

We have shown that overexpression of heme oxygenase-1 (HO-1) prevents the liver inflammation response leading to ischemia and reperfusion injury (IRI). This study was designed to explore the precise function and mechanism of HO-1 cytoprotection in liver IRI by employing a small interfering RNA (siRN...

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Detalhes bibliográficos
Main Authors: Ke, Bibo, Shen, Xiu-Da, Gao, Feng, Qiao, Bo, Ji, Haofeng, Busuttil, Ronald W., Volk, Hans-Dieter, Kupiec-Weglinski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Scientific Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829285/
https://ncbi.nlm.nih.gov/pubmed/19534599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2009.049
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