Adoptive Transfer of Ex Vivo HO-1 Modified Bone Marrow–derived Macrophages Prevents Liver Ischemia and Reperfusion Injury

Macrophages play a critical role in the pathophysiology of liver ischemia and reperfusion (IR) injury (IRI). However, macrophages that overexpress antioxidant heme oxygenase-1 (HO-1) may exert profound anti-inflammatory functions. This study explores the cytoprotective effects and mechanisms of ex v...

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Detalhes bibliográficos
Main Authors: Ke, Bibo, Shen, Xiu-Da, Gao, Feng, Ji, Haofeng, Qiao, Bo, Zhai, Yuan, Farmer, Douglas G, Busuttil, Ronald W, Kupiec-Weglinski, Jerzy W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890105/
https://ncbi.nlm.nih.gov/pubmed/20029397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.285
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