Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia

INTRODUCTION: Autophagy enables cells to recycle long-lived proteins or damaged organelles. Beclin 1, the mammalian orthologue of the yeast Apg6/Vps30 gene, functions as a scaffold for the formation of autophagosomes. MATERIALS AND METHOD: The immunohistochemical patterns of Beclin 1 expression and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Koukourakis, M I, Giatromanolaki, A, Sivridis, E, Pitiakoudis, M, Gatter, K C, Harris, A L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967071/
https://ncbi.nlm.nih.gov/pubmed/20842118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605904
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker