Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival

Hypoxia inducible factors HIF1α and HIF2α are important proteins involved in the regulation of the transcription of a variety of genes related to erythropoiesis, glycolysis and angiogenesis. Hypoxic stimulation results in rapid increase of the HIF1α and 2α protein levels, as a consequence of a redox...

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Autori principali: Giatromanolaki, A, Koukourakis, M I, Sivridis, E, Turley, H, Talks, K, Pezzella, F, Gatter, K C, Harris, A L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2001
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Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375073/
https://ncbi.nlm.nih.gov/pubmed/11556841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2018
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