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A Coiled-Coil Enabled Split-Luciferase Three-Hybrid System: Applied Toward Profiling Inhibitors of Protein Kinases

The 518 protein kinases encoded in the human genome are exquisitely regulated and their aberrant function(s) are often associated with human disease. Thus, in order to advance therapeutics and to probe signal transduction cascades there is considerable interest in the development of inhibitors that...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Jester, Benjamin W., Cox, Kurt J., Gaj, Alicia, Shomin, Carolyn D., Porter, Jason R., Ghosh, Indraneel
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966823/
https://ncbi.nlm.nih.gov/pubmed/20669947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104491h
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